医学科研高通量基因组学视频教程DNA-sep信号通路分析视频生物信息学教学培训视频培训班课程资料

医学科研高通量基因组学视频教程讲解目录

Genetics

provides the building block for the manufacture of allproteins; i.e., hardware

Epigenetics

provides additional instruction on how, when andwhere these information should be used; i.e.,software

Epigenetics

- the study of heritable changes in gene function thatoccur without a change in the DNA sequence

Types of epigeneticmodification

1.DNA methylation

2.Histone modification

3. microRNA

CpG island

- Target of methylation detection- Definition (Takai & Jones)

.CpGs are grouped in clusters called "cpG islands" thatare present in the 5' regulatory regions

 of many genes- Longer than 500 base pair

- G+C content: > 55%

- observed CpG/expected CpG ratio: >= 0.65

1-1微阵列芯片(microarrays)概述【三味教育】.avi

1-2基因表现图谱生物芯片分析【三味教育】.avi

1-3DNA甲基化【三味教育】.avi

1-4miRNA的表达与目标预测【三味教育】.avi

1-5-1单核苷酸多态性(SNP)【三味教育】.avi

1-5-2单核苷酸多态性分析统计【三味教育】.avi

2-1下一代测序(Next-Generation Sequencing，NGS）简介【三味教育】 .avi

2-2使用DNA-sep研究基因组的原理与应用【三味教育】 .av

2-3利用RNA-seq研究转录组学的原理和方法【三味教育】.avi

2-4.下—代测序网络工具及应用【三味教育】.avi

3-1.公用生物芯片资料库【三味教育】.avi

3-2信号通路分析【三味教育】.avi

医学科研高通量基因组学视频教程截图